The University of Havana is located at the beginning of the San Lazaro street, bordered by the street L and the 27 de Noviembre street in Vedado, about 200 meters south to the Hotel Habana Libre.

				
The main campus of the University of 
				Havana, the largest., oldest, and leading academic institution 
				in Cuba, is in Vedado. 
				
In the first half of the 18th century 
				the Dominican friar that were concerned in the education system 
				of the island, requested for the permission to start with the 
				studies in their convent. At that time, children of wealthy 
				families had to go Mexico, Santa Domingo or Spain to receive 
				education. In 1721, the Dominican friars obtained the approval 
				of founding an university in their convent, Convento de San Juan 
				de Letrán, also known as Convento de Santa Domingo, by the bull 
				issued by Pope Innocent XIII. Counts of Bayona had great support 
				in this event.
In 1728 King Philip V of Bourbon 
				confirmed by a Royal Decree the establishment of the Real y 
				Pontificia Universidad de San Gerónimo de La Habana in the 
				renovated convent. This was the first university in Cuba and one 
				of the first universities founded in the Americas. This date is 
				accepted as the date of the establishment of the modern 
				University of Havana today. The university was providing 
				training for theology, philosophy, canons, law, art and medicine 
				at that time.
Except the short period in 1762 in 
				that the invading British army used the building as barracks, 
				many children of wealthy families received education in the 
				fields of laws, medicine, mathematics, grammar, theology and 
				philosophy, attending the five faculties of the university until 
				1841. The prominent personalities of Cuban thought, science and 
				culture that studied in this university are Felix Varela, Manuel 
				de Céspedes, Francisco Vicente Aguilera, Ignacio Agramonte, 
				Francisco de Arango y Parreňo, Tomás Romay, José Augustín 
				Caballero, Antonio Bachiller y Morales, José María Heredia, 
				Rafael María de Mendive, José Antonio Saco and Cirilo Villaverde.
In the course of time, the Dominicans 
				lost their power, and finally also the possession of their 
				property, so that they could not continue with the education 
				that was their main activity as tutors. In 1841 their building 
				passed into the hands of the state, and when the administration 
				of the university was undertaken by the Spanish government, 
				after a process of reforms the university was called Universidad 
				Real y Literaria de La Habana in 1842. It was no longer a 
				religious institution and changed its status to become a 
				secular, royal and literary institution. 
Until the beginning of the 20th 
				century, the university increased its scientific level by adding 
				new faculties. The university graduated the first woman, 
				Mercedes Riba, in 1885. Upon the end of the Spanish rule on the 
				island in 1898, the administration of the university changed 
				hands, so that the most modern teaching methods were initiated. 
				However, the structural condition of the university building in 
				the Convento de San Juan de Letrán was inappropriate. In 1902, 
				the American military government on the island ordered the 
				transfer of some faculties of the university to some buildings 
				on the Hill Aróstegui in Vedado (also known as Loma 
				polytechnics), where it still stays. At the beginning of the 
				republican life, the first buildings on the hill began to be 
				built and the existing ones were adapted to the academic 
				purposes of the university that had received the name of 
				University of Havana.
The founding of the Federación Estudiantil Universitaria (University Student Federation) in 1922 and the inauguration of the staircase in front of the university building in 1928, even though some of the buildings of the university were pending to be constructed, are some of the events that should be mentioned in the first half of the 20th century. In 1956, when the anti-government protests increased in the university, the President Fulgencio Batista closed the university. After the revolution in 1959, the doors of the Havana University were reopened and the education system in the university was reorganized by a set of transformations according the university reform in 1962.